Oncotype DX

Oncotype DX is the first clinically validated commercial genomic assay for patients with DCIS. Oncotype DX reveals the underlying biology that can help guide DCIS treatment decisions by predicting the risk of any local recurrence of breast cancer (DCIS or invasive) and the risk of local invasive carcinoma and allowing for personalized treatment based on tumor biology as determined by the DCIS recurrence score.

Excerpt from “Demystifying DCIS Breast Cancer: Test seeks to predict prognosis and guide treatment decisions,” by Kari Bohlke, ScD, A Woman’s Health:

The Oncotype DX breast cancer test was originally developed for use in certain groups of women with early-stage, invasive breast cancer, but it’s now possible to also use the test to generate a DCIS recurrence score—an indicator of the likelihood that DCIS will recur after treatment with lumpectomy alone.

Read more here: http://dcis411.com/2012/03/11/what-is-oncotype-dx/


2 thoughts on “Oncotype DX”

  1. Kay Singleton said:

    I employed this test to help determine my risk, and couldn’t recommend it more. To the patient, a DCIS score is given to help assess risk. To the doctor, even more info (such as individual markers) can be released and forwarded to the patient. For example, the below article highlights a number of predictive markers. Oncotype DCIS looks at some of these markers and more.

    • Thank you Kay. I agree. A low risk score also helped give me more peace of mind in my decision to forego further surgery and radiation treatment (I had a close margin of .1mm after 2 surgeries). Insurance initially denied, but Genomic Health was so great and easy to work with. They offered me a “patient assistance” program and covered the entire $4,000 test! You must qualify by household income being less than a certain amount. After appeal, my insurance later changed their mind and decided it would cover the test. I thought I would have to pay 10%, but Genomic Health honored their 100% patient assistance coverage which they promised. You may have to ask your Dr. to order this test. They take a sample from your pathology specimen so you don’t have to do anything further. It is another piece of the puzzle that helps individualize risk of recurrence. I am grateful for this test!

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